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Clinical Efficacy and Mechanism of Action of PRP in the Treatment of Osteoarthritis

Clinical Efficacy and Mechanism of Action of Platelet Rich Plasma (PRP) in the Treatment of Osteoarthritis


Regenerative therapy is a treatment method that utilizes cells and growth factors to promote healing and regeneration of damaged or injured tissues, such as bones, cartilage, and tendons. This may include techniques such as stem cell injection, platelet rich plasma, and growth factor therapy to improve recovery after injury or surgery. The goal is to help the body naturally repair tissues and accelerate the healing process to achieve faster and more complete recovery.


In short, PRP obtains a certain amount of plasma rich in growth factors from a certain amount of the patient's blood, which is the plasma used in regenerative therapy.

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The use of platelet rich plasma (PRP) or growth factor rich plasma (PRGF) is a regenerative therapy that utilizes the patient's own platelets and growth factors to promote the repair and regeneration of damaged tissues. PRP or PRGF has been used in various medical and orthopedic fields to treat various diseases and injuries. Some common uses of PRP include:

 

Osteoarthritis: Platelet rich plasma (PRP) is a regenerative therapy increasingly used to treat osteoarthritis, as it shows great therapeutic potential in treating osteoarthritis, especially knee osteoarthritis. The treatment of osteoarthritis significantly reduces pain relief, lightens inflammation, promotes cartilage repair, and improves joint function. In the case of osteoarthritis, PRP is directly injected into the affected joints so that the growth factors contained in PRP can function by helping repair damaged cartilage, reducing inflammation, and relieving pain.

 

Research indicates that the use of PRP in treating knee osteoarthritis yields positive outcomes. Certain studies (cited below) reveal that, compared to injecting hyaluronic acidthe standard therapy for knee osteoarthritisinjecting PRP yields superior results in terms of pain relief and comfort.


Sports injuries - PRP has been employed to treat common sports-related injuries, including ligament tears, tendinitis, and muscle injuries. In such cases, PRP accelerates the healing process and reduces recovery time.


Tendon injuries - PRP has been utilized to address various tendon injuries, such as shoulder rotator cuff tendinitis, lateral epicondylitis (tennis elbow), and Achilles tendinitis.


Cartilage injuries - PRP may potentially facilitate tissue repair and regeneration, aiding in the treatment of joint cartilage injuries, like those found in the knee.


Wound healing - PRP has been applied in wound healing, particularly for chronic ulcers and recalcitrant wounds, by facilitating the growth of new blood vessels and stimulating tissue regeneration.


Beauty and regenerative medicine: In cosmetic medicine, PRP has been employed to treat hair loss, enhance skin texture and quality, and stimulate tissue regeneration during facial rejuvenation procedures.